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Gene Hughes (MD)
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Gene Hughes (MD)   My Press Releases

Fibromyalgia - An Endocannabinoid Deficiency?

Published on 11/21/2018
For additional information  Click Here



Any fibromyalgia patient will tell you that the condition can be quite devastating. The sufferer gets exhausted for doing simple chores like making breakfast or laundry on some days. Commonly characterized by chronic pain, fibromyalgia affects the connective tissues and muscles in the body. That’s why many patients often complain of chronic fatigue, joint stiffness, general weakness, digestive issues, insomnia, headache, cognitive issues, and anxiety.

The National Institute of Health reports that over 5 million Americans are fibromyalgia patients.

For many years, since fibromyalgia disproportionately affected women, those who suffered with its debilitating effects were often labeled as “hysterical women.”

Many doctors would not acknowledge that it was a legitimate disorder and called women hypochondriacs.

It was often referred to as a “psychosomatic disorder.”

Over the years, the medical community has finally recognized it is in fact a physical disorder, but have only speculated as to its underlying cause.

The conventional Western medical treatment consisted of 3 pharmaceuticals, none of which helps with the symptoms, but produces MANY side effects.


The 3 drugs are Lyrica, Cymbalta and Savella.

Some side effects include Suicidal thoughts, Difficulty Concentrating, Weight Gain, Swelling, Hypertension and Nausea

Although pharmaceutical companies are making a lot of money from the manufacture and sale of these medications, they don’t really help patients. That’s why a vast majority of fibromyalgia patients are turning to alternative treatments. 

Cannabidiol or CBD has been anecdotally shown to reduce many of the symptoms of fibromyalgia including pain, fatigue, sleep problems, digestive problems and the mental fog.

With no relief provided by pharmaceuticals, many desperate fibromyalgia sufferers are turning to CBD as a last resort, and have been ecstatic with the results!

There have been patients whom have been so incapacitated by fibromyalgia that they were unable to get out of their beds, let alone work.

Many people have resumed activities that they never expected to ever do again in their lives, including working and exercising. CBD has been literally a “life saver” for so many.



WHY Does it Work??  Well, according to Dr. Ethan Russo, medical director of PHYTECS, is that those who have fibromyalgia suffer from Clinical Endocannabinoid Deficiency (CED). When you replenish the depleted endocannabinoid system with the necessary cannabinoids, the symptoms disappear.

The Endocannabinoid System (ECS) is one of the largest homeostatic systems in the human body, with elements throughout the brain and in every major organ. Scientific research has shown that changes in ECS activity may correlate with a wide range of disease states.

Think of it in similar terms of someone with a Vitamin B deficiency, feeling much better after taking supplements.

For those who have studied the endocannabinoid system (ECS) you will know that its main function is to help the body maintain homeostasis.  When your body is in homeostasis, it is free from disease.

A Survey of 1,339 people with Fybromyalgia conducted by The National Pain Foundation and, revealed that those whom have used Cannabinoids to treat their symptoms found it was significantly more effective than ANY of the three (3) drugs approved by the Food and Drug Administration to treat the disorder.  

The ECS consists of cannabinoid receptors, C1 and C2, which are found in the brain, spinal cord, nerves, the stomach and other organs. It also controls many of our physiological processes such as pain, mood, memory and appetite. When the endocannabinoids are depleted, we experience disorder and disease.

Those with severe fibromyalgia know, only too well, all the symptoms of this disorder. Pain is typically the worst, coupled with incapacitating fatigue. Irritable bowel syndrome and migraine are also very common symptoms. Russo is convinced that this is an indication of ECS deficiency. He purposed this theory as far back as 2001. Recent research studies support this theory with evidence of cannabis usage decreasing pain, improving sleep and relieving gastric distress.

Can CBD alone fight fibromyalgia?


At this point, it’s not possible medically (even legally) to authoritatively answer "yes" to this question. That’s because only a survey by the National Pain Report and a few level 1 studies have been done.  

With that said, scientists and researchers have acknowledged CBD for its strong potential as an anti-inflammatory and a pain-reducing cannabinoid.

Since pain and inflammation are two very common symptoms with Fibromyalgia, one can only assume that CBD is a great option for you. 








These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. CTFO assumes no responsibility for the improper use of and self-diagnosis and/or treatment using these products. Our products should not be confused with prescription medicine and they should not be used as a substitute for medically supervised therapy. If you suspect you suffer from clinical deficiencies, consult a licensed, qualified medical doctor. You must be at least 18 years old to visit our website and make product purchases. We do not make any health claims about our products at CTFO. Before taking our products, it’s wise to check with your physician or medical doctor. It is especially important for people who are: pregnant, chronically ill, elderly, under 18, taking prescription or over the counter medicines. None of the information on our website is intended to be an enticement to purchase and may not be construed as medical advice or instruction. The use of any of our products for any reason, other than to increase general health and wellness, is neither, implied nor advocated by CTFO.

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